Publications by authors named "C P Bartmann"
Purpose: The aim of this study was to investigate the effects of the COVID-19 pandemic on maternal mental health during pregnancy and the postpartum period.
Methods: The impact of the COVID-19 pandemic situation during and post pregnancy was addressed on three main factors; maternal mental health, mother-child bonding, and maternal self-confidence. To do this, two different patient cohorts were compared; data from one cohort was collected pre-pandemic, and data was collected from the other cohort at the beginning of the pandemic.
Purpose: Isolated locoregional recurrence of breast cancer (ILRR) and contralateral breast cancer (CBC) affect up to 20% of all breast cancer (BC) patients in the first 20 years after primary diagnosis. Treatment options comprise surgical interventions and further systemic therapies depending on the histological subtype. Patients with hereditary breast or ovarian cancer (HBOC) undergo MRI, mammography, and ultrasound in the aftercare of BC, while non-HBOC (nHBOC) patients do not regularly receive MRI.
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- The study highlights the importance of understanding sex-specific differences in how women of reproductive age respond to psychopharmaceuticals, particularly given the lack of attention to these variations in clinical trials.
- Blood samples from 27 women with affective disorders were taken during different phases of their menstrual cycle to analyze hormone and drug concentrations, revealing significant fluctuations, especially with the medication bupropion.
- Findings suggest that hormonal changes during the menstrual cycle may impact the effectiveness and safety of psychotropic medications, emphasizing the need for tailored pharmacological treatments for women.
Most cancer patients ultimately die from the consequences of distant metastases. As metastasis formation consumes energy mitochondria play an important role during this process as they are the most important cellular organelle to synthesise the energy rich substrate ATP, which provides the necessary energy to enable distant metastasis formation. However, mitochondria are also important for the execution of apoptosis, a process which limits metastasis formation.
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