The cellular integrity of the kidney in homeostatic regulation has constantly been compromised by oxidative stress following exposure to varying nature of stressor present within the environment. The objective of the work was to evaluate the renal effect of the different stressor stimuli applied. Twenty-four adult female rats weighing averagely 160-200 g and within the ages of 12-14 weeks were used for experiment-1, while 12 offspring were utilized for experiment-2.
View Article and Find Full Text PDFBiomed Pharmacother
November 2021
This study was designed to physiologically investigate the fate of stress related infertility conditions to focus on the regulatory response of reproductive potentials in stress-induced female Wistar rats supplemented with clomifene citrate. 42 apparently healthy female Wistar rats weighing about 120-160 g were used in the study. The animals were randomly distributed into 3 groups after acclimatization for 2 weeks.
View Article and Find Full Text PDFInfertility is generally regarded as a major clinical problem, and it adversely affects people both psychologically and medically. In this study, the changes in gonadal oxidative stress markers and reproductive function of BALB/c mice were investigated. Forty-eight (48) BALB/c mice acquired for this study were randomly divided into four (4) groups of eight (8) mice each.
View Article and Find Full Text PDFCrude ethanolic extracts of the leaves of Sorghum bicolor L. Moench were used as stains for tissue sections. The alkaline mixtures did not stain any of the tissues used but the acidic and neutral alcoholic mixtures stained collagen fibres, muscles and red blood cells in shades of pinkish-yellow.
View Article and Find Full Text PDFMethods Find Exp Clin Pharmacol
June 1997
The vascular effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), a meperidine analog, were studied in vitro on ring preparations of rat aorta for the purpose of characterizing its mode of action. Isometric contractions were evaluated under standard organ bath conditions. Exposure to MPTP (10(-12)-1.
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