Publications by authors named "C P Alexiou"

Magnetic nanoparticles (MNPs) have gained significant attention in biomedical engineering and imaging applications due to their unique magnetic and mechanical properties. With their high magnetization and small size, MNPs serve as excitation sources for magnetically heating to destroy tumors (magnetic hyperthermia) and magnetically controlled drug carriers in magnetic drug targeting. However, effectively visualizing the distribution of MNPs during research or potential clinical use with low-cost modalities remains a critical challenge.

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Article Synopsis
  • - The scapholunate (SL) ligament injury is a common cause of wrist pain and dysfunction, with existing theories exploring its impact on wrist movement lacking sufficient understanding.
  • - A study conducted on 21 fresh-frozen anatomical specimens utilized CT imaging to analyze wrist kinematics after SL ligament transection, focusing on individual carpal bone motion in relation to the radius.
  • - Results indicated a significant increase in palmar rotation of the scaphoid after SL ligament injury during palmar flexion, while other carpal bones were less affected, highlighting the SL ligament's crucial role in wrist biomechanics.
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In clinical situations, peripheral blood accessible CD3CD4CXCR5 T-follicular helper (T) cells may have to serve as a surrogate indicator for dysregulated germinal center responses in tissues. To determine the heterogeneity of T cells in peripheral blood versus tonsils, CD3CD4CD45RACXCR5 cells of both origins were sorted. Transcriptomes, TCR repertoires and cell-surface protein expression were analysed by single-cell RNA sequencing, flow cytometry and immunohistochemistry.

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