Publications by authors named "C Oeser"
Article Synopsis
- The National Surveys of Sexual Attitudes and Lifestyles (Natsal) aim to estimate the prevalence of sexually transmitted infections (STIs) in Britain through biosampling, evaluating methods for acceptability and response rates.
- Two pilot studies were conducted with participants aged 16-59, who provided urine or vaginal swab samples either during face-to-face interviews or remotely, with feedback collected to assess the processes.
- Out of 261 participants, 62% consented to biosampling, with a higher sample return from face-to-face interviews, indicating general acceptability of the biosampling methods used for STI testing in the national survey.
Background: The 2022 Monkeypox virus (MPXV) global outbreak boosted development of multiple serological assays to aid understanding of Mpox immunology.
Objectives: The study aimed to assess a multiplexed solid-phase electrochemiluminescence immunoassay (Meso Scale Discovery (MSD)) for simultaneous detection of antibodies against MPXV, including A35, E8 and M1 antigens, along with corresponding Vaccina Virus (VACV) homologues and demonstrate its accuracy in assessing antibody titres post-vaccination and infection.
Methods: Assay performance was assessed for simultaneous detection of antibodies against MPXV and corresponding VACV antigens.
Article Synopsis
- Early 2022 saw a spike in monkeypox virus infections in the UK, with over 80,000 global cases primarily among gay and bisexual men, prompting public health agencies to offer the IMVANEX Smallpox vaccination to high-risk individuals.
- Researchers developed various ELISA tests to analyze antibody responses from individuals who received different doses of the Smallpox vaccine and those previously infected with MPXV, finding that antibody levels increased with booster doses.
- The study identified specific poxvirus antigens linked to MPXV infection, revealing similar antibody responses in those infected and vaccinated, paving the way for future vaccine and therapeutic advancements.
Poor adherence to TB treatment leads to adverse clinical outcomes. A range of digital technologies to support adherence have been developed and the COVID-19 pandemic considerably accelerated the implementation of digital interventions. Here, we review the current evidence on digital adherence support tools and update the findings of a previous review, with evidence published from 2018 to date.
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