Production of herbal toothpaste: Physical, organoleptic, phyto-compound, and antimicrobial properties.

Objective: To investigate the possibility of producing dental antimicrobial toothpaste from L skin chaff, seed, and pod extracts.

Methods: Ethanolic extracts of the three plant materials were obtained. These were subjected to phytochemical and GC-MS analyses.

Assessment of nutrient contents and bio-functional activities of edible fungus bio-fortified with copper, lithium and zinc.

Bio-enrichment of edible mushrooms is an outstanding strategy to deliver essential nutrients to human. In this study, an edible fungus; Pleurotus pulmonarius was cultivated on spent mushroom substrate (SMS) supplemented with copper, lithium, and zinc. Proximate and mineral analysis of cultivated mushroom was determined using methods of AOAC.

In silico Design of a Vaccine Candidate for SAR S-CoV-2 Based on Multiple T-cell and B-cell Epitopes.

Coronaviruses (2019-nCoV) are large single-stranded RNA viruses that usually cause respiratory infections with a crude lethality ratio of 3.8% and high levels of transmissibility. There is yet no applicable clinical evaluation to assess the efficacy of various therapeutic agents that have been suggested as investigational drugs against the viruses despite their respective supposed hypothetical claims due to their antiviral potentials.

Repositioning of Fungal-based Peptides as Modulators of Angiotensin-converting Enzyme-related Carboxypeptidase, SARS-coronavirus HR2 Domain, and Coronavirus Disease 2019 Main Protease.

Background And Objectives: Angiotensin-converting enzyme-related carboxypeptidase, SARS-Coronavirus HR2 Domain, and COVID-19 main protease are essential for the cellular entry and replication of coronavirus in the host. This study investigated the putative inhibitory action of peptides form medicinal mushrooms, namely , , and , towards selected proteins through computational studies.

Materials And Methods: The respective physicochemical properties of selected peptides were predicted using ProtParam tool, while the binding modes and binding free energy of selected peptides toward proteins were computed through HawkDock server.

Intervention for stress management among skilled construction workers.

Objective: Previous studies have demonstrated the need for a stress management intervention among construction workers. Construction workers, despite their degree of stress, are expected to contribute to the accomplishment of projects on construction sites. This study aimed to ascertain the effect of a group rational emotive behavior therapy (group REBT) on stress management among a select sample of skilled construction workers in construction industry in Nigeria.