Publications by authors named "C O Noble"

Background And Aims: Over the last decade, treatment options for moderate-to-severe ulcerative colitis (UC) have expanded. However, comparative studies between these agents are limited, especially among biologic-naïve patients. We aimed to compare the persistence, effectiveness and safety of tofacitinib and vedolizumab as the first advanced treatment for patients with UC.

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Article Synopsis
  • Targetoid hemosiderotic hemangioma (THH) is a rare vascular lesion that mainly affects adults, usually developing after trauma, with no significant gender preference.
  • The review analyzes THH's characteristics, differentiating it from similar conditions like Kaposi's sarcoma and retiform hemangioendothelioma.
  • Clinically, THH appears as painless lesions with a distinctive target-like look; histologically, it shows specific vascular features and can be identified with immunohistochemical markers.
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Background: Healthcare provider leadership programs represent an intervention opportunity to support advancement of the national system of care and an evaluation of their program impacts is needed. Between 2016 and 2023, the Robert Wood Johnson Foundation (RWJF) funded Clinical Scholars (CS), a three-year equity-centered leadership training program for US healthcare providers. CS recruited participants (referred to as Fellows) in cohorts and engaged them as members of interprofessional teams to transform their careers and the health of their communities.

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Mucormycosis (zygomycosis) is a severe and often fatal mycotic infection affecting primarily immunocompromised individuals. A 61-year-old female with type 2 diabetes mellitus and end-stage renal disease developed septic shock in association with mucormycosis. Despite antifungal treatment with liposomal amphotericin B, the patient's condition rapidly deteriorated, leading to death within 48 hours.

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