Publications by authors named "C Nunez-Alvarez"
Objectives: To evaluate the prevalence and clinical associations of anti-C1q antibodies in IgG4-related disease (IgG4-RD), focusing on renal involvement and cutaneous small-vessel vasculitis (CSVV).
Methods: We enrolled patients who met the revised 2020 Comprehensive Diagnostic Criteria and/or the 2019 ACR/EULAR Classification Criteria for IgG4-RD. Variables included demographics, organ involvement, clinical phenotypes, disease activity, serum biomarkers, follow-up duration, remission, and relapses.
Article Synopsis
- The study focuses on "post-acute COVID-19 syndrome" (PACS), also known as long COVID, which affects a significant portion of survivors, with 37.2% of participants meeting PACS criteria 7-19 months post-infection.
- Researchers examined clinical, immunological, and metabolomic factors in 51 patients and found notable differences in immune responses and metabolite levels associated with PACS.
- Key findings included elevated levels of certain immune cells and metabolites like interleukin-8 and pyruvate in PACS patients, suggesting that these biomarkers during acute infection could help predict the risk of developing PACS.
Article Synopsis
- * A total of 99 adult IIM patients were assessed for various autoantibodies, revealing that 70.7% tested positive for at least one antibody related to CD, while duodenal biopsy confirmed CD in 2% of cases.
- * The study found that specific antibodies (e.g., anti-MDA5 and anti-Mi2) were significantly associated with positive CD serology, highlighting the importance of recognizing IIM patients as a high-risk group for
Objectives: To assess nailfold video capillaroscopic (NVC) abnormalities and their association with clinical features, myositis-specific autoantibodies (MSA), and myositis-associated antibodies (MAA) in a large multi-ethnic cohort of patients with idiopathic inflammatory myopathies (IIM).
Methods: We recruited 155 IIM patients from three centres in Mexico, Spain, and the USA. We evaluated the clinical and laboratory features of the patients and performed semiquantitative and quantitative analyses of the NVC.