Publications by authors named "C Nowak"
Genomic resources are important for evaluating genetic diversity and supporting conservation efforts. The garden dormouse () is a small rodent that has experienced one of the most severe modern population declines in Europe. We present a high-quality haplotype-resolved reference genome for the garden dormouse, and combine comprehensive short and long-read transcriptomics data sets with homology-based methods to generate a highly complete gene annotation.
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- Molecular methods are commonly used for estimating effective population sizes but face challenges due to model assumption violations; simulations and empirical data can help improve these methodologies.* -
- The study analyzed long-term genetic and ecological data of grey wolves in Germany, alongside detailed genetic studies in Poland, Spain, and Portugal, to enhance estimation strategies for these populations.* -
- It was found that the number of wolf packs serves as a reliable indicator of effective population size, and notably, half of the European wolf populations do not meet the effective population size criterion of 500.*
The primary cilium, a single microtubule-based organelle protruding from the cell surface and critical for neural development, also functions in adult neurons. While some dorsal root ganglion neurons elaborate a primary cilium, whether it is expressed by and functional in nociceptors is unknown. Recent studies have shown the role of Hedgehog, whose canonical signaling is primary cilium dependent, in nociceptor sensitization.
View Article and Find Full Text PDFBackground: Step counting is comparable among many research-grade and consumer-grade accelerometers in laboratory settings.
Objective: The purpose of this study was to compare the agreement between Actical and Apple Watch step-counting in a community setting.
Methods: Among Third Generation Framingham Heart Study participants (N=3486), we examined the agreement of step-counting between those who wore a consumer-grade accelerometer (Apple Watch Series 0) and a research-grade accelerometer (Actical) on the same days.