Publications by authors named "C Nishikawa"
Solution-processed inorganic solar cells with less toxic and earth-abundant elements are emerging as viable alternatives to high-performance lead-halide perovskite solar cells. However, the wide range of elements and process parameters impede the rapid exploration of vast chemical spaces. Here, we developed an automated robot-embedded measurement system that performs photoabsorption spectroscopy, optical microscopy, and white-light flash time-resolved microwave conductivity (TRMC).
View Article and Find Full Text PDFObjective: Since 2014, valproate has not been recommended for use in girls and women of childbearing potential unless other treatments are ineffective or not tolerated. Risk minimization measures (RMMs) of valproate were implemented to reduce the potential risks of developmental disorders among pregnant women. A drug utilization study was carried out to assess the effectiveness of RMMs.
View Article and Find Full Text PDFShould beta-blockers be continued as a treatment for myocardial infarction in the case of Kounis syndrome?
Ann Noninvasive Electrocardiol
July 2021
Article Synopsis
- A 71-year-old male experienced anaphylactic shock and was found to be resistant to adrenaline due to his beta-blocker medication, requiring glucagon to stabilize him.
- The patient also developed acute coronary syndrome, leading to the identification of two contributing mechanisms of Kounis syndrome: adrenaline-induced coronary spasm and an imbalance between oxygen supply and demand triggered by the allergic reaction.
- The patient’s beta-blocker treatment was stopped as his heart function remained stable, highlighting the need for careful reconsideration of using beta-blockers after severe allergic events in myocardial infarction recovery.
Comparison of text processing methods in social media-based signal detection.
Pharmacoepidemiol Drug Saf
October 2019
Purpose: Adverse event (AE) identification in social media (SM) can be performed using various types of natural language processing (NLP) and machine learning (ML). These methods can be categorized by complexity and precision level. Co-occurrence-based ML methods are rather basic, as they identify simultaneous appearance of drugs and clinical events in a single post.
View Article and Find Full Text PDFArticle Synopsis
- - Vascular Ehlers-Danlos syndrome (vEDS) is a rare genetic disorder leading to serious vascular issues, like aortic aneurysms, and is diagnosed through molecular testing for COL3A1 mutations.
- - A multi-institutional study analyzed 173 individuals diagnosed with vEDS between 2000 and 2015 to compare those with confirmed COL3A1 mutations against those diagnosed based solely on clinical criteria.
- - Results showed significant differences between the two groups, including a higher percentage of females, different clinical symptoms like joint hypermobility and mitral valve prolapse, and varying rates of other clinical features like easy bruising and thin skin.