Spread Through Air Spaces in Stage I to III Resected Lung Adenocarcinomas: Should the Presence of Spread Through Air Spaces Lead to an Upstaging?

In recent years, the concept of spread through air spaces (STAS) has been discussed as an adverse prognostic factor for lung cancer. The aim of our study is to clarify the prognostic role of STAS in relation to the main recognized prognostic factors in a retrospective cohort of 330 European patients who underwent stages I to III lung adenocarcinoma resection. On univariate analysis, the presence of STAS was related to progression-free survival (PFS; hazard ratio [HR]: 1.

A True Distal Brachial Artery Aneurysm Treated with a Bifurcated Saphenous Vein Graft.

Brachial artery aneurysms are rare, mostly consisting of false ones secondary to infectious, traumatic, or iatrogenic arterial lesions. True aneurysms of the brachial artery are even more uncommon. Here, we report a case of a 40-year-old fisherman, without any pathological antecedent, who presented with a painful pulsatile mass of the left anterior arm.

[Follow-up examination and probatory CPAP therapy of obstructive sleep apnoea increase the long-term compliance].

Introduction: Since the implementation of CPAP therapy in the treatment of obstructive sleep apnoea in the 1980 s researchers have been looking for predictors and possibilities to improve long-term compliance. In a prospective randomised trial we examined the influence of a follow-up examination two weeks after the start of probatory CPAP therapy compared to immediate prescription of the CPAP device.

Methods: 249 new patients with a newly diagnosed obstructive sleep apnoea (OSA) started with a CPAP therapy.