Publications by authors named "C N Papandreou"
Article Synopsis
- A study investigated the metabolic signatures linked to systolic and diastolic blood pressure (BP) and their relationship with cardiovascular diseases (CVD) using data from 201,742 UK Biobank participants and external validation from the Epirus Health Study.
- Researchers found specific metabolites associated with systolic and diastolic BP that correlated with an increased risk of myocardial infarction and CVD, indicating a positive association with elevated BP.
- The study suggests that understanding these metabolic signatures could help elucidate the biological pathways connecting blood pressure to cardiovascular conditions.
Metabolic signature of insulin resistance and risk of Alzheimer's disease.
J Gerontol A Biol Sci Med Sci
November 2024
Article Synopsis
- A study was conducted to explore the link between insulin resistance (IR) and the progression from mild cognitive impairment (MCI) to Alzheimer's disease (AD) dementia in a group of 400 subjects.
- Researchers identified a specific metabolic signature with 18 metabolites that are associated with IR and showed that this signature increases the risk of developing AD dementia.
- The findings suggest that these metabolic pathways could help explain how IR contributes to the development of AD dementia, enhancing our understanding of this relationship.
Exercise improves chronic inflammation and is recommended as a first-line medical or behavioral treatment for OSA with obesity. We examined whether the effects of an exercise program on inflammatory blood markers differed according to severity of OSA among obese adults. Overweight (BMI > 27 kg/m) adults were evaluated for OSA using overnight polysomnography and subsequently classified as exhibiting no-to-mild OSA (AHI < 15 events/hour) or moderate-to-severe OSA (AHI ≥ 15 events/hour).
View Article and Find Full Text PDFPurpose: Infertility is a global health issue and nutrition plays a significant role in fertility outcomes. We aimed to investigate the cross-sectional and prospective associations of glycemic index (GI) and glycemic load (GL) with semen quality parameters in a cohort of healthy young men.
Materials And Methods: The study included 106 men aged 18-35 years from the FERTINUTS trial.
The relationship between bile acids (BAs) and adverse cardiovascular events following acute coronary syndrome (ACS) have been little investigated. We aimed to examine the associations of BAs with the risk of cardiovascular events and all-cause mortality in ACS. We conducted a prospective study on 309 ACS patients who were followed for 10 years.
View Article and Find Full Text PDF