Analgesic activity of certain flavone derivatives: a structure-activity study.

1. Flavone, its methoxy derivatives and flavanone were synthesized by standard methods and were tested for analgesic activity in mice by employing acetic acid writhing and tail flick methods. 2.

Analgesic activity of certain flavone derivatives: a structure-activity study.

Flavone and 10 hydroxy and glucoside flavone derivatives were synthesised. They were tested for their analgesic effect in mice employing acetic acid-induced writhing and tail immersion methods. Subcutaneously all the tested compounds exhibited significant analgesic activity with varying potencies in both assay models.