Publications by authors named "C Murayama"

A 35-year-old woman experienced left back pain after a 2-h flight. She reported coughing and left back pain 1 day later when she presented to our hospital. Chest computed tomography showed pneumothorax of the left lung, bronchiectasis, thickening of the bronchial wall, nodules, and cavity lesions in both lungs.

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Mobile applications are increasingly used in healthcare. We have developed a smartphone healthcare application, , that can register daily diet, exercise, mood, and sleep quality, calculate dietary intake, and provide advice using artificial intelligence technology. This 3-month randomized controlled trial tested the hypothesis that could promote body weight reduction in Japanese adults with overweight or obesity.

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Objective: Mitochondrial dysfunction has been implicated in the pathophysiology of autism spectrum disorder (ASD) in previous studies of postmortem brain or peripheral samples. The authors investigated whether and where mitochondrial dysfunction occurs in the living brains of individuals with ASD and to identify the clinical correlates of detected mitochondrial dysfunction.

Methods: This case-control study used positron emission tomography (PET) with 2--butyl-4-chloro-5-{6-[2-(2-[F]fluoroethoxy)-ethoxy]-pyridin-3-ylmethoxy}-2H-pyridazin-3-one ([F]BCPP-EF), a radioligand that binds to the mitochondrial electron transport chain complex I, to examine the topographical distribution of mitochondrial dysfunction in living brains of individuals with ASD.

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Article Synopsis
  • - The study investigates the link between dopamine D2/3 receptor availability in the brain and social communication symptoms in people with autism spectrum disorder (ASD) using PET and fMRI imaging techniques.
  • - Findings reveal that individuals with ASD have lower D2/3 receptor availability in specific brain areas, particularly the posterior thalamus, which is associated with increased social communication difficulties.
  • - The results support the social motivation hypothesis of autism and suggest potential new targets for therapeutic interventions aimed at improving social communication in individuals with ASD.
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The consumption of dairy products, including milk, may be important for improving the overall quality of a diet. The aim of this study was to examine the relationship between milk intake and nutritional adequacy among Japanese female junior high school students. The participants of this study were Japanese female junior high school students aged between 12 and 15 years.

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