Chromosomal aberrations in iris melanomas.

Background: Uveal melanomas can develop in the choroid, ciliary body and iris. In choroidal and ciliary body melanomas, specific chromosomal changes correlate with metastatic disease. Iris melanomas have a better prognosis than choroidal melanomas, and it would be interesting to know if they share chromosomal changes.

Zipper cell endotheliopathy: a new subset of idiopathic corneal edema.

Purpose: To report the clinical and histologic findings of a new subset of idiopathic corneal edema: zipper cell endotheliopathy.

Design: Observational case report.

Participant: A 55-year-old woman with unilateral bullous keratopathy.

[Waldenstrom's macroglobulinaemia of the lacrimal gland in a patient with sarcoidosis].

We report a case of bilateral lacrimal gland involvement as the first sign of Waldenstrom's macroglobulinaemia in a patient with sarcoidosis. Histological analysis of an incisional biopsy revealed a lymphoplasmocytic lymphoma consistent with Waldenstrom's macroglobulinaemia. No noncaseating granulomas were encountered.