The effective multiplicity of infection for HCMV depends on the activity of the cellular 20S proteasome.

Human cytomegalovirus (HCMV) is a betaherpesvirus capable of infecting numerous cell types and persisting throughout an infected individual's life. Disease usually occurs in individuals with compromised or underdeveloped immune systems. Several antivirals exist but have limitations relating to toxicity and resistance.

Correlation of Sarcopenia with Coronary Artery Disease Severity and Pericoronary Adipose Tissue Attenuation: A Coronary CT Study.

Objective: To investigate the association between sarcopenia, as appraised with CT-derived muscle metrics, and cardiovascular status, as assessed via coronary CT angiography (CCTA) using the Coronary Artery Disease-Reporting and Data System (CAD-RADS) and with pericoronary adipose tissue (pCAT) metrics.

Methods: A retrospective observational study conducted on patients who underwent CCTA. The cross-sectional area (CSA) and attenuation values of the paravertebral muscles at the T8 level and the pectoralis major muscles at the T6 level were measured.

Diagnostic performance of an artificial intelligence model for the detection of pneumothorax at chest X-ray.

Purpose: Pneumothorax (PTX) is a common clinical urgency, its diagnosis is usually performed on chest radiography (CXR), and it presents a setting where artificial intelligence (AI) methods could find terrain in aiding radiologists in facing increasing workloads. Hence, the purpose of our study was to test an AI system for the detection of PTX on CXR examinations, to review its diagnostic performance in such setting alongside that of reading radiologists.

Method: We retrospectively ran an AI system on CXR examinations of patients who were imaged for the suspicion of PTX, and who also underwent computed tomography (CT) within the same day, the latter being used as reference standard.

The effective multiplicity of infection for HCMV depends on activity of the cellular 20S proteasome.

Unlabelled: Human cytomegalovirus (HCMV) is a betaherpesvirus capable of infecting numerous cell types and persisting throughout an infected individual's life. Disease usually occurs in individuals with compromised or underdeveloped immune systems. Several antivirals exist but have limitations relating to toxicity and resistance.

The GREENWATER study: patients' green sensitivity and potential recovery of injected contrast agents.

Objectives: The environmental footprint of iodinated contrast agents (ICAs) and gadolinium-based contrast agents (GBCAs) is noteworthy. This study assesses: (1) patients' "green sensitivity" as measured by their acceptance in a sustainability study and (2) the resulting potential reduction of contrast residuals in wastewater.

Materials And Methods: After ethical approval, participants scheduled for administration of ICAs or GBCAs for diagnostic purposes were enrolled in this prospective observational study from July 2022 to October 2023.