Characterisation of the submarine disposal of a Bayer effluent (Gardanne alumina plant, southern France): III: Trace metals in the seawater column in the vicinity of the discharge area in the Mediterranean Sea.

In the context of evaluating the environmental impact of deep-sea tailing practices, we conducted a case study on the Bayer effluent released into the Mediterranean Sea by the French Gardanne alumina plant. This effluent results from the filtration of red mud, which has previously been discharged into the Cassidaigne canyon for 55 years. In 2015, regulatory changes permitted the released of a filtered effluent instead of the slurry.

The Use of Arts-Based Methods to Enhance Patient Engagement in Health Research.

Introduction: Patient and care partner engagement in research (PER) is important in generating knowledge to improve healthcare. Arts-based methods (ABM) use art in the research process to share aesthetic knowledge, which is knowledge that may be too complex to share only verbally. Together, PER and ABM are potentially synergistic, as both are participatory, problem-focused, dialogic, and collaborative; yet little is known of the utility of ABM for PER.

Caregiving in long-term care before and during the COVID-19 pandemic: a scoping review.

Purpose: The COVID-19 pandemic magnified pre-existing socioeconomic, operational, and structural challenges in long-term care across the world. In Canada, the long-term care sector's dependence on caregivers as a supplement to care workers became apparent once restrictive visitation policies were employed. We conducted a scoping review to better understand the associations between caregiving and resident, formal and informal caregiver health in long-term care before and during the COVID-19 pandemic.

A scoping review of incidence and assessment tools for post-intensive care syndrome following cardiac surgery.

Background: Post-intensive care syndrome is a new or worsening persistent deterioration in cognitive, mental, and/or physical health following a prolonged admission to an intensive care unit. Post-intensive care syndrome remains underexplored following cardiac surgery, with a lack of understanding of the incidence and tools used to measure the symptoms. A scoping review was conducted to determine the incidence and to identify the tools commonly used to measure symptoms of post-intensive care syndrome following cardiac surgery.

The Rtf1/Prf1-dependent histone modification axis counteracts multi-drug resistance in fission yeast.

RNA polymerase II transcription elongation directs an intricate pattern of histone modifications. This pattern includes a regulatory cascade initiated by the elongation factor Rtf1, leading to monoubiquitylation of histone H2B, and subsequent methylation of histone H3 on lysine 4. Previous studies have defined the molecular basis for these regulatory relationships, but it remains unclear how they regulate gene expression.