Publications by authors named "C Mitsuhata"
Background: Hypophosphatasia (HPP) is an inherited disease caused by low activity of tissue-nonspecific alkaline phosphatase. Dental characteristics include premature loss of primary teeth, enlarged pulp chambers, and enamel hypoplasia. Although enzyme replacement therapy with asfotase alfa was approved in 2015, there are few reports about the dental outcomes of this treatment.
View Article and Find Full Text PDF: Generative artificial intelligence (AI) such as ChatGPT has developed rapidly in recent years, and in the medical field, its usefulness for diagnostic assistance has been reported. However, there are few reports of AI use in dental fields. : We created 20 questions that we had encountered in clinical pediatric dentistry, and collected the responses to these questions from three types of generative AI.
View Article and Find Full Text PDFBackground/purpose: Artificial intelligence (AI) has developed rapidly and is applied to many fields including dental education. In this study, we evaluated AI performance on the Japanese National Dental Examination.
Materials And Methods: We extracted 349 of 400 compulsory questions from the National Dental Examinations over the past five years.
Eruption Disturbance in Children Receiving Bisphosphonates: Two Case Reports.
Pharmaceuticals (Basel)
November 2024
Background: Bisphosphonates used for the treatment of osteoporosis, hypercalcemia, or heterotopic calcifications can cause serious adverse dental events such as osteonecrosis of the maxillary and mandibular bones. However, the effects in childhood remain scarcely explored.
Case Presentations: We encountered two children who had started bisphosphonate therapy before completion of the primary dentition.
Article Synopsis
- Red complex bacteria are highly virulent in periodontal disease, and this study focused on their relationships with other oral bacteria in older Japanese individuals.
- Polymerase chain reaction was used to analyze dental plaque from 116 subjects, finding that individuals positive for red complex bacteria had significantly higher detection rates of certain periodontal pathogens compared to those who were negative.
- The findings indicate that individuals harboring all three red complex species have a unique oral microbiome, showcasing greater α-diversity and lower β-diversity, suggesting they may be more prone to developing periodontal disease.