MRI-based score for acute basilar artery thrombosis.

Background: Intra-arterial thrombolysis may reduce mortality in acute basilar artery (BA) occlusion. We wanted to identify an easy-to-use pre-treatment MR-based predictor of clinical outcome in patients with acute BA occlusion treated with IAT.

Methods: We analyzed 16 patients with acute BA occlusion prospectively.

[Ethics and animal experimentation. The ethics committees in France and foreign countries].

Functions, main features, organization and operating principles of ethical committees for animal experiments in France and foreign countries are presented from a general viewpoint. Four majors concepts are underlined: awareness of respect of animal, competence, open door policy, communication.

Hormonal response to restraint in rhesus monkeys.

The purpose of this study was to characterize the hormonal responses to a restraining system in four adult male rhesus monkeys (Macaca mulatta) in preparation for a spaceflight project. After the monkeys were accustomed to food and water (Phase I), blood-volume-regulating hormones were measured during three phases: 10 days in a metabolic cage (Phase II), 16 days sitting in a restrained position in a specially designed metabolism chair (Phase III) and 10 days in metabolic cage (Phase IV). An increase of active renin (30%) and vasopressin (25%) was observed at the end of Phase III.

A restraining system for rhesus monkeys used in space research.

A new chronic restraining system has been designed specifically for male rhesus monkeys (8-13 kg) housed in weightlessness for scientific purposes. The restraining system consists of a coat (jacket and skirt) and a chair. The system separates the thorax from the lower part of the body, and allows large movements of the upper part of the body.

The effects of a 5-month physical training on iliac bone morphology in monkeys.

The present study was designed to provide data on the effects on bone of 5 months of daily exercise in nonhuman primates. The subjects were five male rhesus monkeys with mature skeletons with a body mass of 8-10 kg. The exercise schedule selected to provide endurance training was a daily continuous 1-h climbing task.