Publications by authors named "C Mico"
Article Synopsis
- A registry analysis was conducted on adult acute myeloid leukemia (AML) patients in remission who underwent haplo-hematopoietic stem cell transplant (HSCT) between 2010 and 2020, comparing thiotepa, busulfan, and fludarabine (TBF) versus treosulfan (Treo) conditioning.
- The study included 1123 patients, with 968 receiving TBF and 155 receiving Treo, and a matched-pair analysis was performed on 142 patients from each group to assess outcomes.
- No significant differences were found in terms of graft-versus-host disease incidence, nonrelapse mortality, or leukemia-free survival between the two conditioning
We conducted a retrospective multicenter study including pediatric and adult patients with acute leukemia (AL) who received donor lymphocyte infusions (DLIs) after allogeneic hematopoietic stem cell transplantation (HCT) between January 1, 2010 and December 31, 2015, in order to determine the efficacy and toxicity of the immune treatment. Two hundred fifty-two patients, median age 45.1 years (1.
View Article and Find Full Text PDFWe analyzed the impact of alloHSCT in a single center cohort of 89 newly diagnosed AML patients, consecutively treated according to the Northern Italy Leukemia Group protocol 02/06 [NCT00495287]. After two consolidation cycles, the detection of measurable residual disease (MRD) by RQ-PCR was strongly associated with an inferior three-year overall survival (OS, 45% versus 84%, = 0.001) and disease-free survival (DFS, 44% versus 76%, = 0.
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