Publications by authors named "C Michailides"
: The increased prevalence of antibiotic resistance among Gram-negative bacteria presents a severe public health challenge, leading to increased mortality rates, prolonged hospital stays, and higher medical costs. In Greece, the issue of multidrug-resistant Gram-negative bacteria is particularly alarming, exacerbated by overuse of antibiotics and inadequate infection control measures. This study aimed to detect the prevalence of extensively drug-resistant (XDR) Gram-negative bacteria in a tertiary hospital in Western Greece over the last eight years from 2016 to 2023.
View Article and Find Full Text PDFArticle Synopsis
- A Gram-negative coccobacillus from the normal oral flora of pets, particularly cats and dogs, is primarily known for causing soft tissue infections from bites or scratches.
- The bacterium is infrequently but increasingly reported as a cause of prosthetic joint infections (PJIs), with only a few documented cases since 1992.
- This article describes a case of a 67-year-old woman who developed a hip infection from this bacterium after total hip arthroplasty, successfully treated with surgery and antibiotics, while also reviewing related literature on PJIs from this pathogen.
Article Synopsis
- - Acute pancreatitis (AP) is a serious condition primarily treated with supportive measures, and understanding the role of inflammasomes, particularly the NLRP3 type, has improved our knowledge of its inflammatory processes.
- - The NLRP3 inflammasome facilitates inflammation in AP through various activation methods and signaling pathways, making it an attractive target for new treatments aimed at controlling inflammation.
- - While preclinical studies show promise for NLRP3 inhibitors in reducing inflammation and improving outcomes in AP, there is a significant lack of clinical trials to test their effectiveness and safety in humans, highlighting the need for further research.
Background: COVID-19 related syndromes are not yet well described and understood. Multisystem inflammatory syndrome of the adults (MIS-A) is a recently characterized syndrome affecting multiple organs of young adults, causing serious complications, even shock and death.
Objectives: To determine the clinical characteristics, course, and complications of MIS-A in a systematic way and summarize currently used treatments.
Introduction: Patients being on immunosuppressive treatment of any reason, along with other risk factors such as smoking and obesity, are vulnerable to be infected from SARS-CoV2. Aim of this report is to describe a case of a female patient under Rituximab therapy who experienced episodes of lung infection due to Severe Acute Coronavirus 2 (SARS-CoV-2 ) invasion although fully vaccinated.
Case Report: A 50-year-old woman, with a past medical history of lupus nephritis on rituximab was diagnosed with lung infection due to SARS-CoV-2.