Population Genomics of Adaptive Radiation.

Adaptive radiations are rich laboratories for exploring, testing, and understanding key theories in evolution and ecology because they offer spectacular displays of speciation and ecological adaptation. Particular challenges to the study of adaptive radiation include high levels of species richness, rapid speciation, and gene flow between species. Over the last decade, high-throughput sequencing technologies and access to population genomic data have lessened these challenges by enabling the analysis of samples from many individual organisms at whole-genome scales.

Decision analysis of Integrated Pest Management: A case study on invasive sea lamprey in the Great Lakes Basin.

Integrated Pest Management (IPM) provides a powerful framework for addressing threats to human well-being caused by nuisance species including invasives. We examined the hypothesis that adaptive management could erode barriers to IPM implementation by developing a decision-analytic adaptive management framework for invasive sea lamprey (Petromyzon marinus) IPM in the Laurentian Great Lakes of North America. The framework addressed objectives associated with coordinating multiple sea lamprey control actions at the regional scale and objectives associated with internal validity of control actions.

A Comparison of Endoscope-Assisted and Open Frontoorbital Distraction for the Treatment of Unicoronal Craniosynostosis.

Background: Frontoorbital distraction osteogenesis (FODO) is an established surgical technique for patients with unicoronal craniosynostosis. The authors' institution has used an endoscope-assisted technique (endo-FODO) in recent years to decrease cutaneous scarring and lessen the impact on the functional growth matrix. This study compared perioperative outcomes in patients undergoing endo-FODO to those in patients undergoing the traditional coronal approach.

Endoscopic-assisted versus open fronto-orbital distraction for unicoronal craniosynostosis: morphometric and technique considerations.

Introduction: In an effort to maximize benefit and minimize morbidity when performing fronto-orbital distraction osteogenesis (FODO) for unilateral coronal synostosis (UCS), we have transitioned to an endoscopic-assisted approach ("endo-FODO"). This study compares photogrammetric outcomes of patients who underwent FODO via an endoscopic-assisted versus open approach.

Methods: We retrospectively reviewed patients treated for UCS from 2013 to 2023.

Synergistic label-free fluorescence imaging and miRNA studies reveal dynamic human neuron-glial metabolic interactions following injury.

Neuron-glial cell interactions following traumatic brain injury (TBI) determine the propagation of damage and long-term neurodegeneration. Spatiotemporally heterogeneous cytosolic and mitochondrial metabolic pathways are involved, leading to challenges in developing effective diagnostics and treatments. An engineered three-dimensional brain tissue model comprising human neurons, astrocytes, and microglia is used in combination with label-free, two-photon imaging and microRNA studies to characterize metabolic interactions between glial and neuronal cells over 72 hours following impact injury.