Publications by authors named "C Michael Valentine"

Article Synopsis
  • After allogeneic hematopoietic cell transplantation (HCT), only a small fraction of donor stem cells help reconstitute the recipient's blood system, while the donor maintains a nearly normal stem cell pool.
  • Researchers studied blood samples from 16 donor-recipient pairs, focusing on potential clonal hematopoiesis (CH) variants that could arise due to extra stress on donor cells post-transplant.
  • Results showed similar mutation rates in both donors and recipients, with a small percentage of shared variants showing a significant increase in recipients over time, indicating that the human hematopoietic system has strong regenerative abilities even many years after HCT.
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Background: Plant-based formulas have become increasingly popular due to their health benefits, environmental concerns, cultural beliefs, improved palatability, and decreased cost. A retrospective chart review of medically stable children transitioning from a hypoallergenic formula to a yellow pea protein plant-based formula (PPPBF) was included. This study aimed to assess gastrointestinal tolerance, weight changes, and adherence to receiving a unique PPPBF.

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Preterm birth is the leading cause of neonatal and under-5 mortality globally, and healthcare-related burden and nutrition-related morbidities are unsustainable, particularly in resource-limited regions. Additionally, preterm infants are susceptible to multiple adverse outcomes including growth faltering, suboptimal neurodevelopment, and multisystemic morbidities. Maturation, healing, repair, and restoration to normalcy in preterm-born infants require optimizing nutrition; only then, prognosis, growth, neurodevelopment, and overall quality of life can improve.

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