Getting ahead of human-associated microbial decline in Africa: the urgency of sampling in light of epidemiological transition.

Evidence is growing that human-associated early-life microbial diversity modulates health over the long term, via effects in the infant termed 'immune and metabolic education'. Documenting high microbial diversity contexts, such as in Africa, thus, has rich potential for understanding this aspect of the landscape of health. Yet, change on the continent is occurring rapidly, and microbial communities are shifting as behaviors and diets are altered, and antibiotic use expands; we may be losing the opportunity to obtain relevant data.

Intersecting Memories of Immunity and Climate: Potential Multiyear Impacts of the El Niño-Southern Oscillation on Infectious Disease Spread.

Climate and infectious diseases each present critical challenges on a warming planet, as does the influence of climate on disease. Both are governed by nonlinear feedbacks, which drive multi-annual cycles in disease outbreaks and weather patterns. Although climate and weather can influence infectious disease transmission and have spawned rich literature, the interaction between the independent feedbacks of these two systems remains less explored.

A foundation systematic review of natural language processing applied to gastroenterology & hepatology.

Objective: This review assesses the progress of NLP in gastroenterology to date, grades the robustness of the methodology, exposes the field to a new generation of authors, and highlights opportunities for future research.

Design: Seven scholarly databases (ACM Digital Library, Arxiv, Embase, IEEE Explore, Pubmed, Scopus and Google Scholar) were searched for studies published between 2015 and 2023 that met the inclusion criteria. Studies lacking a description of appropriate validation or NLP methods were excluded, as were studies ufinavailable in English, those focused on non-gastrointestinal diseases and those that were duplicates.

Characterizing the evolution of defense in a tripartite marine symbiosis using adaptive dynamics.

The evolution and maintenance of symbiotic systems remains a fascinating puzzle. While the coevolutionary dynamics of bipartite (host-symbiont) systems are well-studied, the dynamics of more complex systems have only recently garnered attention with increasing technological advances. We model a tripartite system inspired by the marine symbiotic relationship between the alga sp.

RSero: A user-friendly R package to reconstruct pathogen circulation history from seroprevalence studies.

Population-based serological surveys are a key tool in epidemiology to characterize the level of population immunity and reconstruct the past circulation of pathogens. A variety of serocatalytic models have been developed to estimate the force of infection (FOI) (i.e.