Publications by authors named "C Mesnard"
Synaptotagmin-9 (Syt9) is a Ca sensor mediating fast synaptic release expressed in various parts of the brain. The presence and role of Syt9 in retina is unknown. We found evidence for Syt9 expression throughout the retina and created mice to conditionally eliminate Syt9 in a cre-dependent manner.
View Article and Find Full Text PDFPhotocoagulation or sham laser in addition to conventional anti-VEGF therapy in macular edema associated with TelCaps due to diabetic macular edema or retinal vein occlusion (TalaDME): a study protocol for a multicentric, French, two-group, non-commercial, active-control, observer-masked, non-inferiority, randomized controlled clinical trial.
Trials
April 2024
Article Synopsis
- Macular edema (ME) occurs due to leakage from retinal blood vessels, which can lead to serious vision loss, and current treatments like intravitreal injections (IVIs) are costly and burdensome.
- The TalaDME study investigates whether a targeted laser treatment (ICG-guided targeted laser - IGTL) combined with standard IVI reduces the number of injections needed within the first year while maintaining visual acuity.
- This French multicentric trial involves 270 patients with ME linked to diabetic retinopathy or retinal vein occlusion, randomly assigning them to either standard care or the combined treatment to evaluate the effectiveness of laser photocoagulation on reducing injection frequency and improving visual outcomes.
Introduction: Dengue is an arboviral disease transmitted by the dengue virus, whose vectors are Aedes aegypti and Aedes albopictus. The acute phase with its cohort of well-known symptoms is usually spontaneously favorable. Since 2020 in Reunion Island, a new symptom has appeared: the ocular damage of dengue fever, which has already been described in South Asia and South-East Asia.
View Article and Find Full Text PDFSynaptotagmin-9 (Syt9) is a Ca sensor mediating fast synaptic release expressed in various parts of the brain. The presence and role of Syt9 in retina is unknown. We found evidence for Syt9 expression throughout the retina and created mice to conditionally eliminate Syt9 in a cre-dependent manner.
View Article and Find Full Text PDF