Publications by authors named "C Meschini"

: Periprosthetic joint infections (PJIs) have emerged as a focal point in the realm of orthopedics, garnering widespread attention owing to the escalating incidence rates and the profound impact they impose on patients undergoing total joint arthroplasties (TJAs). Year after year, there has been a growing trend in the analysis of multiple risk factors, complication rates, and surgical treatments in the field. This study aims to illuminate the status of the sex-related differences in periprosthetic joint infections and advance research in this field.

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: Long bones are commonly affected by musculoskeletal tumors, but they also represent one of the most frequent locations for metastases. The treatment is based on pain management and the prevention or stabilization of pathological fractures by intramedullary nailing. While titanium nails are probably the most used, carbon-fiber-reinforced (CFR) nails have emerged as a new option for oncological patients.

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Background: Unicompartmental Knee Arthroplasty (UKA) is a valuable solution for the treatment of medial osteoarthritis of the knee. New implants feature designs for the elective substitution of a specific compartment. Aim of this study was to assess the survivorship and functional outcomes at minimum 4 years of the first 60 implanted patients in a pilot center of a new medial UKA as the evolution of a well performing long lasting fixed bearing implant.

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Article Synopsis
  • The study compared the safety and effectiveness of etanercept and adalimumab biosimilars (SB4 and ABP501) with their original versions among patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis in Italy from 2017 to 2020.
  • Out of 891 patients, safety profiles were similar; however, biosimilars had higher discontinuation rates due to ineffectiveness, with retention rates at 24 months being 76.5% for biosimilars compared to 81.1% for originators.
  • The findings suggest biosimilars are a viable, safe, and more affordable treatment option, offering
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Article Synopsis
  • This study validated the Sunderland Tracheoesophageal Perceptual Scale (SToPS) in Italian to assess its reliability among different raters, focusing on laryngectomized patients with voice prosthesis.
  • The validation process included translating the scale, gathering data from 60 patients and 12 healthcare professionals, and evaluating speech samples through perceptual assessments and statistical analysis.
  • Results indicated that experienced speech-language therapists had better reliability in ratings, achieving a good level of agreement, which confirms the Italian SToPS as a reliable assessment tool for tracheoesophageal voice.
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