Publications by authors named "C Menetrey"
Purpose: The aim of the study was to analyze the characteristics of otherwise healthy children with obstructive sleep apnea (OSA; OSA-I) and children with OSA and non-syndromic obesity (OSA-II) treated with long term continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV) in 2019 in France.
Methods: Data were collected from a national survey on paediatric home noninvasive ventilatory support. CPAP/NIV initiation criteria and duration, age at CPAP/NIV initiation, equipment used and CPAP/NIV settings, and objective compliance were analyzed.
Article Synopsis
- Ravidasvir (RDV) is a new drug that effectively inhibits the hepatitis C virus (HCV) replication and has shown promising results when combined with Sofosbuvir (SOF) in trials involving adults, including those co-infected with HIV.
- In a study conducted in Thailand and Malaysia, RDV was given to both patients with and without cirrhosis for various durations, and pharmacokinetics (how the drug behaves in the body) were evaluated through blood sampling at different intervals.
- The analysis revealed that RDV levels were influenced by several factors; however, these variations were not significant enough to impact the drug's effectiveness across the diverse group of participants, and there were no significant drug interactions for
Rationale: The use of long-term noninvasive respiratory support is increasing in children along with an extension of indications, in particular in children with central nervous system (CNS) disorders.
Objective: The aim of this study was to describe the characteristics of children with CNS disorders treated with long-term noninvasive respiratory support in France.
Methods: Data were collected from 27 French pediatric university centers through an anonymous questionnaire filled for every child treated with noninvasive ventilatory support ≥3 months on 1st June 2019.
The aim of the study was to describe the characteristics of children with neuromuscular diseases treated with long term noninvasive ventilation or continuous positive airway pressure in France. On June 1st 2019, 387 patients (63% boys, mean age 11.2 ± 5.
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- Hereditary angioedema (HAE) is a serious condition causing unpredictable swelling attacks, and over the past decade, new treatments for long-term prophylaxis (LTP) have emerged based on a better understanding of its biology.
- A study conducted in France in 2020 surveyed physicians from 25 expert centers about their practices, treatments, and the unmet needs of HAE patients; ultimately focusing on 20 centers with active patient files.
- Of the 714 patients with C1 inhibitor deficiency, 59.2% were on LTP, but many still faced unmet needs related to treatment tolerability, efficacy, and cost; physicians expressed a desire for more effective, better-tolerated, and affordable therapies