Publications by authors named "C Meier Magistretti"
Maternal and newborn plasma oxytocin levels in response to maternal synthetic oxytocin administration during labour, birth and postpartum - a systematic review with implications for the function of the oxytocinergic system.
Sarah Buckley Kerstin Uvnäs-Moberg Zada Pajalic Karolina Luegmair Anette Ekström-Bergström Claudia Meier Magistretti
BMC Pregnancy Childbirth
March 2023
Article Synopsis
- * Aim: The study aims to systematically review the effects of synthetic oxytocin on the oxytocin levels in mothers and newborns during and after labor, examining potential impacts on their natural hormone systems.
- * Results: Administration of synthetic oxytocin significantly increased maternal levels in a dose-dependent manner, with higher rates achieving levels 2-3 times normal. Newborns showed elevated oxytocin levels, which were notably higher in the umbilical artery than in the umbilical vein, indicating active production by the fetus during labor.
Maternal plasma levels of oxytocin during physiological childbirth - a systematic review with implications for uterine contractions and central actions of oxytocin.
Kerstin Uvnäs-Moberg Anette Ekström-Bergström Marie Berg Sarah Buckley Zada Pajalic Claudia Meier Magistretti
BMC Pregnancy Childbirth
August 2019
Article Synopsis
- Oxytocin is essential for childbirth, with synthetic versions commonly used to help induce or speed up labor, which led researchers to review its levels in mothers during natural childbirth and in response to synthetic infusions.
- A systematic search of medical databases was conducted, resulting in 20 studies that met the criteria, and the data was analyzed to assess oxytocin's effects during and after childbirth.
- Findings showed that oxytocin levels significantly increase during pregnancy and labor, with multiple pulses occurring as labor progresses, indicating complex regulation of uterine contractions and suggesting a role for oxytocin in both physical and psychological processes during birth.
Background: Health care outcomes used in service evaluation and research tend to measure morbidity and mortality. This is the case even in maternity care, where most women and babies are healthy. Salutogenesis theory recognises that health is a continuum, with explicit inclusion of well-being as well as illness and pathology.
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