Pediatric Resuscitative Thoracotomy in Infants, Children, and Early Adolescents: A Scoping Review.

Introduction: Recent publications sought to define the role of resuscitative thoracotomy (RT) in the pediatric population; however, few studies guide its use in young children and infants. This review characterizes the presentation and outcomes of patients ≤15 y old undergoing RT.

Methods: A scoping review querying publications in PubMed, Embase, and Scopus prior to March 2024 was conducted using Covidence software.

Effect of mono-guanidine-like derivatives on platelet aggregation and tumour cell induced platelet aggregation.

Antiplatelet agents are the cornerstone for the treatment and prevention of cardiovascular diseases. However, they can induce severe side effects such as gastrointestinal bleeding. The main aim of this study is to determine the effect that novel guanidine-based derivatives exert on platelet aggregation.

Endothelial cell Pannexin1 overexpression impairs ischemic stroke outcome in a sex-dependent manner.

Ischemic stroke is a leading cause of morbidity and mortality. We have previously shown that deletion of endothelial cell (EC) Panx1 reduces ischemic stroke infarct volume and reduces cerebral arterial myogenic reactivity, which regulates cerebral blood flow. We hypothesized that EC Panx1 content dictates ischemic stroke outcome and thus increased EC Panx1 expression will worsen ischemic stroke outcomes due to exacerbated myogenic tone development and impaired cerebral blood flow recovery.

First trimester universal one-time serology screening for cytomegalovirus. A pilot study at two tertiary referral centers in Barcelona (Catalunya, Spain).

Introduction Congenital cytomegalovirus (cCMV) is the main infectious cause of sensorineural hearing loss and neurodevelopmental disability. First-trimester and periconceptional period are the most vulnerable times for fetal injury. Universal serological cytomegalovirus (CMV) screening in pregnant women is not currently recommended.

Use of photon-counting CT and three-dimensional printing for an intra-thoracic retained ballistic fragment in a 9-year-old.

Retained ballistic fragments from gunshot wounds pose diagnostic and management challenges for radiologists and surgeons alike. Imaging and clinical decision-making regarding removal warrant comprehensive risk/benefit discussions, considering anatomic location, complexity of surgical removal, and risk of long-term complications of bullet migration and potential lead toxicity. Herein, we describe a 9-year-old with a retained intra-thoracic para-aortic ballistic fragment causing elevated lead levels.