Publications by authors named "C McDonough"

Per- and polyfluoroalkyl substances (PFAS) are widely used persistent synthetic chemicals that have been linked to adverse health effects. While the behavior of PFAS has been evaluated in the environment, our understanding of reaction products in mammalian systems is limited. This study identified biological PFAS transformation products and generated mass spectral libraries to facilitate an automated search and identification.

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  • Mycotoxin contamination in corn is a significant risk factor for poultry production, with common mycotoxins including fumonisin (FUM), deoxynivalenol (DON), aflatoxin (AFB1), and zearalenone (ZEA) detected in all corn samples studied.
  • Almost all samples (81.71%) contained multiple mycotoxins, with 38.41% showing two, 36.59% showing three, and 4.88% showing all four types of mycotoxins.
  • The study found that different mycotoxins impacted the nutrient content of corn differently, affecting levels of fat, starch, protein, and moisture, indicating that co-contamination
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  • Improving the control of hypertension is crucial for public health, but accurately identifying uncontrolled hypertension using electronic health records (EHR) is challenging across different health systems.
  • A retrospective study analyzed EHR data from two health systems—Yale-New Haven Health System and OneFlorida Clinical Research Consortium—covering adult patients with hypertension from October 2015 to December 2018 to assess their blood pressure control status.
  • The study found that a significant percentage of patients had uncontrolled hypertension, with notably higher rates among Black patients compared to White patients, highlighting disparities in hypertension management.
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