Mogamulizumab is a humanized monoclonal antibody with enhanced antibody-dependent cell-mediated cytotoxicity that targets chemokine receptor type. Several clinical trials and real-life experiences confirmed the efficacy and safety profiles of mogamulizumab as second-line therapy and beyond, and the biochemical- and dermatology-specific quality of life and physical functioning, with high treatment satisfaction. Systemic drugs are usually used in patients with resistant or advanced forms of cutaneous T-cell lymphomas (especially mycosis fungoides) or with Sézary Syndrome, while early-stage mycosis fungoides can be managed at least initially with local treatments.
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February 2025
Dupilumab, a monoclonal antibody targeting the IL-4/13 signaling pathway, effectively treats moderate-to-severe atopic dermatitis (AD). Common side effects include injection site reactions, conjunctivitis, and respiratory infections. We report the case of a 28-year-old woman with severe AD involving the periocular and chin regions, genital areas, arms, and legs (Eczema Area and Severity Index [EASI]: 24, itch Visual Analog Scale [VAS]: 8) who showed significant improvement after initiating dupilumab therapy.
View Article and Find Full Text PDFSocial media platforms have become integral to healthcare communication, particularly in dermatology, where visual assessment and patient education are paramount. While platforms like Instagram, Facebook, and Twitter offer significant opportunities to raise awareness about skin health, promote preventive measures, and encourage early detection of dermatological conditions, the unregulated dissemination of health information poses substantial risks due to misinformation. In response to these challenges, the Italian Association of Hospital Dermatologists (ADOI) has launched a nationwide survey titled "Use of Social Media by Dermatology Professionals: Impact on Public Awareness, Appropriateness of Information, and Correctness of Prevention Messages-An Italian Survey".
View Article and Find Full Text PDFSkin cancer incidence is increasing worldwide. Clear communication between dermatologists and histopathologists, along with the possibility of sharing clinical images, is critically important. This survey aims to depict the level of communication between dermatologists and histopathologists in clinical practice in Italy.
View Article and Find Full Text PDFPurpose Of Review: Arboviral infections caused by Dengue, Zika, and Chikungunya viruses continue to pose a significant global health threat, particularly in endemic regions. This review is timely because of the increasing prevalence of these infections, driven by factors such as urbanization and climate change. Dermatological manifestations of these viruses are crucial for early diagnosis, especially given the overlap in symptoms, which can complicate differential diagnosis.
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