Publications by authors named "C Masse"

Article Synopsis
  • BECTS is a type of epilepsy in children that can harm thinking skills, especially when it's worsened by another condition called ESES.
  • The study looked at brain activity in kids with BECTS-ESES and compared it to healthy kids to see how their brains connect and if it was related to their learning problems.
  • Researchers found that kids with BECTS-ESES had different brain connections that could explain why they struggle with things like memory and attention, highlighting the importance of the Salience Network in understanding their cognitive issues.
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Sarcoidosis and systemic sclerosis are two inflammatory multisystemic disorders of unknown etiology that may be life-threatening especially when there is cardiac involvement. Both diseases may coexist, however, there are very few case reports of patients with both cardiac sarcoidosis and systemic sclerosis in the literature. We report the case of a 72-year-old female who was initially referred for dyspnea.

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Background: Vaccination protects against severe COVID-19 manifestations. For those with post-COVID-19 conditions (PCC) or long COVID, the impact of COVID-19 vaccination on the evolution of symptoms, immune responses, and viral persistence is unclear.

Methods: In this prospective observational cohort study, we evaluated the number of PCC symptoms, affected organ systems, and psychological well-being scores before and after patients with PCC received COVID-19 vaccination.

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Article Synopsis
  • A new species of polyclad flatworm, described from Arcachon Bay, France, is classified as a new genus based on both morphological and molecular analyses.
  • The molecular analysis indicates that this new genus is the second of the Idioplanidae family and is closely related to the Latocestidae family and certain genera.
  • The findings suggest that this flatworm species might originate from an Indonesian or Indo-Pacific family, with a particular feeding habit on oysters and mussels in Arcachon farms.
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TYK2 is a key mediator of IL12, IL23, and type I interferon signaling, and these cytokines have been implicated in the pathogenesis of multiple inflammatory and autoimmune diseases such as psoriasis, rheumatoid arthritis, lupus, and inflammatory bowel diseases. Supported by compelling data from human genome-wide association studies and clinical results, TYK2 inhibition through small molecules is an attractive therapeutic strategy to treat these diseases. Herein, we report the discovery of a series of highly selective pseudokinase (Janus homology 2, JH2) domain inhibitors of TYK2 enzymatic activity.

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