Publications by authors named "C Marx"

Article Synopsis
  • The study explores the biological differences linked to PTSD by examining DNA methylation changes in blood, suggesting they could indicate susceptibility or effects of trauma.
  • Conducted by the Psychiatric Genomics Consortium, the research included nearly 5,100 participants to identify specific genetic markers associated with PTSD.
  • Results showed 11 significant CpG sites related to PTSD, with some also showing correlations between blood and brain tissue methylation, highlighting their potential role in understanding PTSD biology.
View Article and Find Full Text PDF

Acute sprains and ruptures of the lateral ankle ligaments are the most common injuries of the ankle joint. They are often related to sporting activity and predominantly affect individuals under 40 years old. Lateral ligament injuries occur due to supination trauma.

View Article and Find Full Text PDF

Accurate uncertainty estimates are important in sequential model-based decision-making tasks such as Bayesian optimization. However, these estimates can be imperfect if the data violates assumptions made by the model (e.g.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the link between post-traumatic stress disorder (PTSD) and differences in DNA methylation, a type of gene regulation, in blood samples from individuals diagnosed with PTSD compared to trauma-exposed controls.
  • Researchers conducted a large-scale analysis involving over 5,000 participants from various civilian and military studies, using standardized procedures for PTSD assessment and DNA methylation testing.
  • The results revealed 11 specific DNA methylation sites associated with PTSD, and found similarities in methylation patterns between blood and brain tissues, suggesting a biological basis for the condition.
View Article and Find Full Text PDF