Publications by authors named "C Martinez-Reglero"

Article Synopsis
  • Hepatocellular carcinoma, a leading cause of cancer deaths, is primarily treated with sorafenib, and this study evaluates its effectiveness and toxicity in real-world settings.
  • A total of 36 patients were studied, revealing an average overall survival of 8.5 months and common adverse effects including constitutional, gastrointestinal, and dermatological issues.
  • The results indicate that while survival outcomes in clinical practice align with clinical trials, the toxicity profile showed unexpected variations.
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Background: Nowadays, good clinical practice should be established in human research. Patient's rights and autonomy must be respected above the interest of the researcher, making mandatory to raise patient's awareness on the implications of participating in a clinical study. Contrary to popular belief, this is not always the case.

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Coronary artery disease (CAD) is a common chronic condition in the elderly. However, the earlier CAD begins, the stronger its impact on lifestyle and costs of health and social care. The present study analyzes clinical and angiographic features and the outcome of very young patients undergoing coronary angiography due to suspected CAD, including a nested case-control study of ≤40-year-old patients referred for coronary angiography.

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Coronary artery disease is a chronic disease with an increased expression in the elderly. However, different studies have shown an increased incidence in young subjects over the last decades. The prediction of major adverse cardiac events (MACE) in very young patients has a significant impact on medical decision-making following coronary angiography and the selection of treatment.

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Background: The declaration of the first state of alarm for COVID-19 in March 2020 provoked changes in ophthalmological care. The objective of this study was to assess its impact on reorganising care activities, the mental health of ophthalmologists and the training of residents.

Methods: We sent an anonymous online questionnaire between August and October 2020 to consultant ophthalmologists and residents who were active during the state of alarm in Spain.

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