Publications by authors named "C Martinez Vicente"

Since December 2019, a new form of Severe Acute Respiratory Syndrome (SARS) has emerged worldwide, caused by SARS coronavirus 2 (SARS-CoV-2). This disease was called COVID-19 and was declared a pandemic by the World Health Organization in March 2020. Symptoms can vary from a common cold to severe pneumonia, hypoxemia, respiratory distress, and death.

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The global resurgence of syphilis has created a potent stimulus for vaccine development. To identify potentially protective antibodies against Treponema pallidum (TPA), we used Pyrococcus furiosus thioredoxin (PfTrx) to display extracellular loops (ECLs) from three TPA outer membrane protein families (outer membrane factors for efflux pumps, eight-stranded β-barrels, and FadLs) to assess their reactivity with immune rabbit serum (IRS). We identified five immunodominant loops from the FadL orthologs TP0856, TP0858 and TP0865 by immunoblotting and ELISA.

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Background: In 2019, a dengue outbreak involving Aedes albopictus occurred in a rural area of Espírito Santo, Brazil, motivating our study in Sooretama and Linhares.

Methods: We set traps to sample immature mosquito larvae at 40 sites, with weekly inspections from July 2022 to January 2023. Adult specimens were collected monthly at 19 sites, each collection lasting 15 min.

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Article Synopsis
  • Pine wilt disease, caused by the pinewood nematode Bursaphelenchus xylophilus, poses significant risks to global pine forests, and its management presents logistical challenges and ecological concerns.
  • Esteya spp., specifically Esteya vermicola and Esteya floridanum, show promise as biological control agents against the nematode, with studies evaluating their competitive abilities against other fungi and their metabolic capabilities.
  • Results indicate both Esteya spp. effectively suppress the pinewood nematode in lab settings, suggesting that applying these fungi to pine trees could enhance their protection against the nematode and related fungal pathogens.
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Article Synopsis
  • Syphilis, caused by a spirochetal pathogen, can lead to serious health complications if untreated, necessitating new strategies to understand its complex pathogenesis.
  • This study engineered a strain of the syphilis bacteria that expresses green fluorescent protein (GFP), allowing researchers to visualize its interactions with host cells and evaluate its infectivity in a rabbit model.
  • The findings emphasize the role of specific antibody responses in targeting the bacteria's outer membrane, highlighting potential targets for protective immunity and paving the way for future research on spirochetal-host interactions.
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