Publications by authors named "C Martin-Gandul"
Article Synopsis
- Elderly individuals in chronic care facilities are at a higher risk of infections from multidrug-resistant organisms (MDROs), prompting the need for effective antimicrobial stewardship programs (ASPs).
- A comprehensive review of 134 studies from 1987 to 2020 showed varying prevalence rates of specific MDROs in long-term care facilities (LTCFs) globally, with Asia having the highest rates of extended-spectrum β-lactamase (ESBL) and North America seeing significant rates of multidrug resistance (MDR).
- Key risk factors for MDRO acquisition include male sex, chronic wounds, use of medical devices, and prior antibiotic use, with the latter being a critical target for intervention through ASPs in LTCFs.
Background: Long-term care facilities (LTCFs) are health-care settings with high antimicrobial consumption and hence need to develop effective antimicrobial stewardship programmes (ASPs).
Objective: To assess the effects of ASPs on care-related, clinical and ecological outcomes in LTCFs.
Methods: Data sources were PubMed, EMBASE, CINAHL and SCOPUS.
Objectives: The genus Enterobacter is a common cause of nosocomial infections. Historically, the most frequent Enterobacter species were those of Enterobacter cloacae complex and Enterobacter aerogenes. In 2019, E.
View Article and Find Full Text PDFA Randomized, Double-Blind, Placebo-Controlled Trial (TAURCAT Study) of Citrate Lock Solution for Prevention of Endoluminal Central Venous Catheter Infection in Neutropenic Hematological Patients.
Carlota Gudiol Montserrat Arnan Manuela Aguilar-Guisado Cristina Royo-Cebrecos Isabel Sánchez-Ortega
Antimicrob Agents Chemother
January 2020
Article Synopsis
- Long-term central venous catheters (CVCs) can lead to infections in cancer patients, prompting a study to compare a treatment (taurolidine-citrate-heparin) to a placebo in preventing infections in high-risk neutropenic patients.
- A trial with 150 patients found that while the taurolidine-citrate-heparin solution led to slightly less bacterial colonization compared to the placebo (4.1% vs. 10.1%), the results were not statistically significant and did not impact secondary infection rates or adverse events.
- The study concluded that despite showing some potential in reducing hub colonization, taurolidine-citrate-heparin did not provide a clear benefit over placebo, suggesting further research