Bone Mineral Status in Children and Adolescents with Klinefelter Syndrome.

Objective. Klinefelter syndrome (KS) has long-term consequences on bone health. However, studies regarding bone status and metabolism during childhood and adolescence are very rare.

Bone mineral status and metabolism in patients with Williams-Beuren syndrome.

Objective: To evaluate bone mineral status and metabolism in a cohort of patients with Williams-Beuren syndrome (WBS).

Patients: Thirty-one children (15 females, 16 males; mean age 9.6±2.

Determinants of Vitamin D Levels in Italian Children and Adolescents: A Longitudinal Evaluation of Cholecalciferol Supplementation versus the Improvement of Factors Influencing 25(OH)D Status.

Objective. This paper aims to assess 25(OH)D levels in Italian children and adolescents identifying risk factors for 25(OH)D deficiency and to evaluate whether a normal 25(OH)D value can be restored in 25(OH)D-deficient patients. Methods.

Diabetes mellitus in a girl with thyroid hormone resistance syndrome: a little recognized interaction between the two diseases.

The syndrome of resistance to thyroid hormone (RTH) is characterized by elevated serum free thyroid hormones (FT4 and FT3) in the presence of unsuppressed TSH levels, reflecting resistance to the normal negative feedback mechanisms in the hypothalamus and pituitary. The degree of resistance within peripheral tissues determines whether thyrotoxic clinical features are associated with this condition. Classic features include attention deficit hyperactivity disorder, growth delay, tachycardia, and goiter.

Increased risk of coeliac disease in patients with congenital hypothyroidism.

Background: In patients with congenital hypothyroidism (CH), the presence of coeliac disease (CD) has been sporadically described.

Methods: Seventy-nine consecutive children (58 females and 21 males; age range 3.1-12.