Publications by authors named "C Mancusi"

Purpose: The delayed or missed diagnosis of secondary hypertension contributes to the poor blood pressure control worldwide. This study aimed to assess the diagnostic approach to primary aldosteronism (PA) and pheochromocytoma (PHEO) among Italian centers associated to European and Italian Societies of Hypertension.

Methods: Between July and December 2023, a 10-items questionnaire was administered to experts from 82 centers of 14 Italian regions and to cardiologists from the ARCA (Associazioni Regionali Cardiologi Ambulatoriali) Piemonte.

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  • This study examines how the growth and calcification of the appendicular skeleton in the Raja asterias affects its movement in water, highlighting the link between bone structure and fin mechanics.
  • It identifies two growth patterns—crustal in larger skeletal parts and catenated in fin radials—showing how differences in development can influence fin flexibility and locomotion.
  • The results suggest that unique calcification patterns, especially in the pelvic fins, evolve to meet the mechanical needs of swimming, emphasizing the adaptability of Batoidea fins through their joint structures and specialized designs.
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Background: Sodium-Glucose Cotransporter-2 inhibitors (SGLT2i) represent a deep revolution of the therapeutic approach to heart failure (HF), preventing its insurgence but also improving the management of the disease and slowing its natural progression. To date, few studies have explored the effectiveness of SGLT2i and, in particular, Dapagliflozin in a real-world population. Therefore, in this observational prospective study, we evaluated Dapagliflozin's effectiveness in a real-world HF population categorized in the different hemodynamic profiles.

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  • Cardiac resynchronization therapy (CRT) is commonly used for heart failure patients, but its compatibility with cardiac magnetic resonance (CMR) imaging is uncertain.
  • This study aimed to evaluate the safety of a "CRT off-on" protocol during CMR and to observe its immediate effects on left ventricular (LV) function.
  • Results showed that while the protocol was generally safe, only a few patients had analyzable data, and while there were improvements in LV function, technical issues highlight the need for better methods during CRT imaging.
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