Rational Design of Porous Organic Framework (POF) for Efficient Conversion of CO to Cyclic Carbonates and 2-Oxazolidinones at Atmospheric Pressure Conditions.

Carbon dioxide (CO) capture and its subsequent catalytic fixation into usable compounds represent a potential approach for addressing the energy problem and the implications of global warming. Hence, it is necessary to develop effective catalytic systems required for the transformation of CO into valuable chemicals/fuels. Herein, we rationally designed a hydroxyl-functionalized porous organic framework (OH-POF) consisting of both acidic (OH) as well as basic N sites for the transformation of CO using epoxides for the production of cyclic carbonates (CCs), a useful commodity chemical under environmental-friendly, metal/solvent/co-catalyst-free conditions.

Differential encoding of mammalian proprioception by voltage-gated sodium channels.

Animals requiring purposeful movement for survival are endowed with mechanoreceptors, called proprioceptors, that provide essential sensory feedback from muscles and joints to spinal cord circuits, which modulates motor output. Despite the essential nature of proprioceptive signaling in daily life, the mechanisms governing proprioceptor activity are poorly understood. Here, we identified nonredundant roles for two voltage-gated sodium channels (Nas), Na1.

Non-Noble Metal Anchored 2D Covalent Organic Framework for Ambient CO Fixation to High-Value Compounds.

The catalytic functionalization of CO into high-value compounds comprises a promising approach to mitigate its atmospheric content and sustainable generation of fine chemicals. In this respect, covalent organic frameworks (COFs) offer great potential in carbon dioxide capture and utilization. Herein, we report application of a crystalline, nanoporous 2D COF (ET-BP-COF) obtained by condensation of 4,4',4'',4'''-(ethene-1,1,2,2-tetrayl) tetraaniline (ET-NH) and 2,2'-bipyridyl-5,5'-dialdehyde (BP-CHO) building blocks for strategic utilization of CO.

Differential encoding of mammalian proprioception by voltage-gated sodium channels.

Animals that require purposeful movement for survival are endowed with mechanosensory neurons called proprioceptors that provide essential sensory feedback from muscles and joints to spinal cord circuits, which modulates motor output. Despite the essential nature of proprioceptive signaling in daily life, the mechanisms governing proprioceptor activity are poorly understood. Here, we have identified distinct and nonredundant roles for two voltage-gated sodium channels (Nas), Na1.

Pyrene-Based Nanoporous Covalent Organic Framework for Carboxylation of C-H Bonds with CO and Value-Added 2-Oxazolidinones Synthesis under Ambient Conditions.

The selective carbon capture and utilization (CCU) as a one-carbon (C1) feedstock offers dual advantages for mitigating the rising atmospheric CO content and producing fine chemicals/fuels. In this context, herein, we report the application of a porous bipyridine-functionalized, pyrene-based covalent organic framework (Pybpy-COF) for the stable anchoring of catalytic Ag(0) nanoparticles (NPs) and its catalytic investigation for fixation of CO to commodity chemicals at ambient conditions. Notably, Ag@Pybpy-COF showed excellent catalytic activity for the carboxylation of various terminal alkynes to corresponding alkynyl carboxylic acids/phenylpropiolic acids via C-H bond activation under atmospheric pressure conditions.