Publications by authors named "C M Uslenghi"
Introduction: We aimed to assess our 25-year experience in order to evaluate the role of adjuvant chemotherapy in patients who undergo pneumonectomy for pN1 NSCLC.
Materials And Methods: We retrospectively reviewed the outcomes and medical records of patients undergoing pneumonectomy for NSCLC with pathological diagnosis of pN1, excluding all patients who underwent neoadjuvant treatment. We compared patients treated with adjuvant chemotherapy with patients who did not undergo neoadjuvant treatment during a follow-up soon after surgery.
Article Synopsis
- Pneumonectomy, a major surgical procedure for treating pulmonary neuroendocrine tumors like carcinoid tumors, requires careful planning due to its high morbidity and mortality risks.
- A study analyzed 21 patients who underwent pneumonectomy over 21 years, finding a 65.4% five-year survival rate, with a median hospital stay of eight days and no perioperative deaths.
- The results suggest that pneumonectomy can be an effective treatment for low-grade malignancies, with the importance of radical lymph node dissection highlighted for improving patient outcomes and survival rates.
Objective: This study aimed at describing our high-volume single center experience in robotic-assisted thoracic surgery (RATS) to evaluate short outcome and feasibility of the technique, the adequacy of oncological results, and the learning curve.
Methods: We retrospectively analyzed data from 1000 consecutive patients who underwent lobectomy and systematic lymphadenectomy for primary lung cancer using RATS approach between May 2007 and May 2023.
Results: Nine-hundred ninety-seven patients (99.
Pulmonary cancer is often associated with systemic inflammation and poor nutritional status and these two aspects are strongly correlated and related to the scarce infiltration of a tumor by immune cells. We reviewed all English literature reviews from 2000 to 2024 from PubMed, Scopus and Google Scholar, including original articles, review articles, and metanalyses. We excluded non-English language articles and case reports/case series.
View Article and Find Full Text PDFLung cancer, a multifaceted disease, demands tailored therapeutic approaches due to its diverse subtypes and stages. This comprehensive review explores the intricate landscape of lung cancer research, delving into recent breakthroughs and their implications for diagnosis, therapy, and prevention. Genomic profiling and biomarker identification have ushered in the era of personalised medicine, enabling targeted therapies that minimise harm to healthy tissues while effectively combating cancer cells.
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