Publications by authors named "C M Sergi"

Hepatic fibrinogen storage disease is an uncommon autosomal dominant hereditary illness marked by hypofibrinogenemia and the accumulation of variant fibrinogen in the hepatic endoplasmic reticulum. We present an asymptomatic 15-month-old male with elevated liver enzymes. Test results indicate hypofibrinogenemia.

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Article Synopsis
  • Extrarenal teratoid Wilms' tumor (TWT) is a rare type of cancer with complex histology, making diagnosis challenging; the case discussed involves an 8-year-old girl with a mediastinal mass containing nephroblastomatous elements.
  • Surgical resection revealed a mature cystic teratoma mixed with nephroblastoma, and immunohistochemical tests confirmed the diagnosis, leading to a smooth recovery for the patient.
  • This case emphasizes the importance of detailed histopathological analysis in distinguishing TWT from other tumors, underlining the necessity for long-term monitoring due to potential recurrence.
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Importance: Extensive research has found the detrimental health effects of heat waves. However, a critical gap exists in understanding their association with adverse health events among older dually eligible individuals, who may be particularly susceptible to heat waves.

Objective: To assess the association between heat waves and adverse health events among dually eligible individuals 65 years and older.

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In this work, five different dextran-based cryogels for controlled drug release are investigated. Vitamin B12 was used as a model drug for in vitro release tests. Two different drug-loading procedures were adopted, leading to very different drug release curves.

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