Introduction: Effective treatment of breast cancer remains a formidable challenge, partly due to our limited understanding of the complex microenvironmental factors that contribute to disease pathology. Among these factors are tissue-resident perivascular cells, which play crucial roles in shaping vascular basement membranes, maintaining vessel integrity, and communicating with adjacent endothelial cells. Despite their essential functions, perivascular cells have been relatively overlooked.
View Article and Find Full Text PDFDiazotrophic cyanobacteria can overcome nitrogen (N)-limitation by fixing atmospheric N; however, this increases their energetic, iron, molybdenum, and boron costs. It is unknown how current and historic N-supplies affect cyanobacterial elemental physiology beyond increasing demands for elements involved in N-fixation. Here, we examined the changes in pigment concentrations, N-storage, and the ionome (i.
View Article and Find Full Text PDF. Intracortical microelectrode arrays often fail to deliver reliable signal quality over chronic recordings, and the effect of an implanted recording array on local neural circuits is not completely understood..
View Article and Find Full Text PDFPurpose: To evaluate an adolescent-centered pregnancy options counseling curriculum for pediatric residents.
Methods: In 2022, we assessed the curriculum in one residency by randomizing half the residents to a pretraining or posttraining Observed Structured Clinical Exam (OSCE). We scored the OSCE by 15-item rubric and analyzed results by Wilcoxon Rank-Sum tests.