Publications by authors named "C M Richter"
Chitosans are versatile biopolymers with antimicrobial and plant-strengthening properties relevant to agriculture. However, a limited understanding of molecular structure-function relationships and cellular modes of action of chitosans hampers the development of effective chitosan-based agro-biologics. We partially hydrolyzed a chitosan polymer (degree of polymerization DP 800, fraction of acetylation F 0.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how multimodal treatment affects progression-free survival (PFS) and overall survival (OS) for patients with multiple localizations of glioblastoma, a rare and aggressive brain tumor.* -
- Researchers analyzed data from 483 glioblastoma patients, finding that the extent of surgical resection significantly predicts both PFS and OS, and that various treatment strategies improved outcomes.* -
- The results indicate that patients with multiple lesions can achieve similar survival rates as those with a single tumor when receiving aggressive, comprehensive treatment.*
Article Synopsis
- - The study investigates the psychosocial protective factors that may help adults with congenital heart disease (ACHD) manage post-traumatic stress symptoms (PTSS), highlighting the importance of resilience, sense of coherence, and social support.
- - Data from 234 ACHD patients revealed that a stronger sense of coherence and better social support significantly lowered PTSS, while low resilience increased the risk of developing these symptoms.
- - The findings emphasize the need for early parental and social support, and suggest that screening for these resources could guide vulnerable patients toward better care, ultimately improving their psychosocial well-being and quality of life.
. To compare in reproducible and equalized conditions the performance of two independent proton range verification systems based on prompt gamma-ray detectors from two different proton therapy centers..
View Article and Find Full Text PDFArticle Synopsis
- Metabolism significantly influences cancer progression, with a focus on glucose as a key energy source, while the role of other natural sugars is less understood.
- This study used advanced 2D NMR spectroscopy to analyze the metabolism of C-labelled sugars (glucose, fructose, galactose, mannose, and xylose), revealing that mannose mimics glucose’s metabolic profile, and galactose plays a crucial role in one-carbon metabolism alongside fructose.
- The findings indicate that cancer cells utilizing fructose or galactose show reduced sensitivity to certain inhibitors, suggesting these sugars are essential in understanding metabolism in cancer treatments.