Publications by authors named "C M Regan"

: The burden of scoliosis care extends beyond treatment costs and includes missed school for patients and lost income for parents. Chronic absenteeism, defined as more than 18 days of missed school, can have a significant impact on a child's educational progression, but missed school and work due to scoliosis treatment are not well quantified in the literature. This study investigates absenteeism among scoliosis patients and their caregivers.

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  • The study aims to analyze how self-regulation is understood and utilized within occupational therapy literature, spanning from 2000 to mid-2023.
  • Using systematic review methods, 4,159 articles were screened, resulting in the inclusion of 64 studies that provided insights into the concept of self-regulation.
  • Content analysis identified five key constructs related to self-regulation, highlighting inconsistencies in how these concepts are defined and measured in occupational therapy practices.
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Background: The use of surveillance technologies is becoming increasingly common in inpatient mental health settings, commonly justified as efforts to improve safety and cost-effectiveness. However, their use has been questioned in light of limited research conducted and the sensitivities, ethical concerns and potential harms of surveillance. This systematic review aims to (1) map how surveillance technologies have been employed in inpatient mental health settings, (2) explore how they are experienced by patients, staff and carers and (3) examine evidence regarding their impact.

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Intraspecific variation is necessary for evolutionary change and population resilience, but the extent to which it contributes to either depends on the causes of this variation. Understanding the causes of individual variation in traits involved with reproductive timing is important in the face of environmental change, especially in systems where reproduction must coincide with seasonal resource availability. However, separating the genetic and environmental causes of variation is not straightforward, and there has been limited consideration of how small-scale environmental effects might lead to similarity between individuals that occupy similar environments, potentially biasing estimates of genetic heritability.

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  • The study focuses on developing new sulfone analogues of known metallo-β-lactamase inhibitors (MBLis) and their antibacterial effectiveness.
  • The new compounds showed greater effectiveness in killing gram-negative bacteria when paired with antibiotics imipenem and relebactam.
  • Improved antibacterial activity is linked to stronger enzyme-inhibitor interactions and decreased bacterial cell efflux, as shown by experiments with different strains of Pseudomonas aeruginosa.
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