Publications by authors named "C M Mattana"
Article Synopsis
- A study analyzed the 6-month outcomes of patients with COVID-19 who received either helmet noninvasive ventilation (NIV) or high-flow nasal oxygen for respiratory failure, focusing on safety and recovery.
- Of the 80 patients alive at follow-up, results showed no significant differences in vital signs, physical performance, respiratory function, or quality of life between the two treatment groups, although fewer patients in the helmet group reported joint pain.
- Patients who required intubation had significantly worse lung function compared to those who managed to avoid it, highlighting the critical nature of respiratory support in hypoxemic cases.
Microbial secondary infections can contribute to an increase in the risk of mortality in COVID-19 patients, particularly in case of severe diseases. In this study, we collected and evaluated the clinical, laboratory and microbiological data of COVID-19 critical ill patients requiring intensive care (ICU) to evaluate the significance and the prognostic value of these parameters. One hundred seventy-eight ICU patients with severe COVID-19, hospitalized at the S.
View Article and Find Full Text PDFMicrobial resistance to antibiotics affects the control of clinical infections and is a growing concern in global public health. One important mechanism whereby micro-organisms acquire resistance is biofilm formation. This context has led to the investigation of new antimicrobial substances from plants popularly used in folk medicine.
View Article and Find Full Text PDFPurpose: The aim of this study is to provide a prospective analysis of post-operative and oncological outcomes in patients affected by locally advanced rectal cancer (LARC), who obtained a major/complete clinical response after pre-operative radio-chemotherapy (RCT) and were treated with local excision (LE) by trans-anal endoscopic microsurgery (TEM) to confirm a pathological complete response (pCR) after to neo-adjuvant RCT.
Methods: All patients with LARC treated by pre-operative RCT and full-thickness LE by TEM (2000-2014) were included in the study. If the pathological analysis confirmed near complete or pCR, intensive follow up was proposed.
Background: The aim of this study was to identify stage II colon cancer patients with a high risk of recurrence.
Methods: All patients who underwent surgery for stage II colon cancer (CC) were retrospectively enrolled and sub-grouped according to TNM staging (IIa-b-c) and stage IIa in high (IIaHR) and low risk (IIaLR) according to pathologic features. The primary outcomes measured were the 5-year overall survival (OS) and disease-free survival (DFS).