Publications by authors named "C M Mangione"

Scientists from diverse backgrounds are underrepresented (UR) in academia. This lack of diversity impedes scientific discovery and innovation. UR scientists tend to conduct research on issues relevant to UR populations, including chronic disease prevention and management, and health disparities.

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Spinal muscular atrophy (SMA) is a pediatric genetic disorder characterized by the loss of spinal cord motor neurons (MNs). Although the mechanisms underlying MN loss are not clear, current data suggest that glial cells contribute to disease pathology. We have previously found that SMA astrocytes drive microglial activation and MN loss potentially through the upregulation of NF-κB-mediated pro-inflammatory cytokines.

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Background: The University of California's Diabetes Prevention Program (UC DPP) Initiative was implemented systemwide to address diabetes and obesity risk on all 10 campuses. As little is known about implementing lifestyle change programs in university settings, we examined implementation partners' (i.e.

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Article Synopsis
  • Breast cancer is the second most common cancer among U.S. women, with 43,170 estimated deaths in 2023, and there are disparities in incidence and mortality rates based on race.
  • The USPSTF aimed to analyze the effectiveness of various mammography screening strategies related to age, intervals, and methods to determine their impact on breast cancer outcomes.
  • The USPSTF recommends biennial mammogram screenings for women aged 40 to 74 years but finds insufficient evidence to recommend screening for women 75 and older or to assess additional screening methods like ultrasound or MRI.
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Background: The University of California's Diabetes Prevention Program (UC DPP) Initiative was implemented across all 10 UC campuses in 2018. The COVID-19 pandemic and accompanying mandates required swift changes to program delivery, including pivoting from in-person to virtual delivery (i.e.

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