Publications by authors named "C M Kremer"
Objectives: Spinal cord stimulation (SCS) therapy is an effective treatment for chronic pain, particularly in conditions such as postlaminectomy syndrome and complex regional pain syndrome (CRPS). Rare case reports described significant weight loss in patients who underwent dorsal column SCS therapy for chronic pain. Recently, neuromodulation for obesity has become a novel field for research.
View Article and Find Full Text PDFBackground: Compared to ischemic stroke, sex differences in patient outcomes following intracerebral hemorrhage (ICH) are underreported. We aimed to determine sex differences in mortality and functional outcomes in a large, unselected Swedish cohort.
Methods: In this observational study, data on 22,789 patients with spontaneous ICH registered in the Swedish Stroke Register between 2012 and 2019 were used to compare sex differences in 90-day mortality and functional outcome using multivariable Cox and logistic regression analyses, adjusting for relevant confounders.
The present study investigated the effects of a driver monitoring system that triggers attention warnings in case distraction is detected. Based on the EuroNCAP protocol, distraction could either be long glances away from the forward roadway (≥3s) or visual attention time sharing (>10 cumulative seconds within a 30 s time interval). In a series of manual driving simulator drives, 30 participants completed both driving related tasks (e.
View Article and Find Full Text PDFParvalbumin-expressing inhibitory neurons (PVNs) stabilize cortical network activity, generate gamma rhythms, and regulate experience-dependent plasticity. Here, we observed that activation or inactivation of PVNs functioned like a volume knob in the mouse auditory cortex (ACtx), turning neural and behavioral classification of sound level up or down over a 20dB range. PVN loudness adjustments were "sticky", such that a single bout of 40Hz PVN stimulation sustainably suppressed ACtx sound responsiveness, potentiated feedforward inhibition, and behaviorally desensitized mice to loudness.
View Article and Find Full Text PDFArticle Synopsis
- The study assesses the inclusion of sex and gender analysis in medical research on stroke and dementia in the Asia-Pacific region from 2012 to 2022, revealing a need for improvements in this area.
- While the overall number of publications in brain health research increased, the proportion focusing on sex and gender analysis remained stagnant, indicating a lack of progress over the decade.
- Findings suggest that gender of authors may influence the inclusion of such analyses, with female authors being more likely to focus on sex and gender, but overall efforts to integrate these perspectives in research remain inadequate.