Publications by authors named "C M KUNIN"
Suppression of Infection With Bismuth Subsalicylate: Was It the Bismuth or the Salicylate?
Open Forum Infect Dis
August 2022
Background: Whether the non-inferior efficacy and safety results of switching virologically suppressed HIV-1-infected patients from nevirapine immediate-release (NVP-IR) to NVP extended-release (NVP-XR) demonstrated in the TRANxITION study conducted in Europe and North America are also applicable to virologically suppressed HIV-infected Taiwanese patients remains unknown. We evaluated the comparative safety and efficacy of continuing NVP-IR versus switching to NVP-XR in virologically suppressed HIV-infected Taiwanese adults receiving combined antiretroviral therapy (cART) regimens.
Methods: We conducted a retrospective cohort study at Kaohsiung Veterans General Hospital from April 1, 2013, to March 31, 2015.
Background: Cellulitis is a common infectious disease. Although blood culture is frequently used in the diagnosis and subsequent treatment of cellulitis, it is a contentious diagnostic test. To help clinicians determine which patients should undergo blood culture for the management of cellulitis, a diagnostic scoring system referred to as the Bacteremia Score of Cellulitis was developed.
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- Trimethoprim/sulfamethoxazole (TMP/SMX) is the top treatment for Pneumocystis jirovecii pneumonia (PJP) in AIDS patients, but it frequently causes adverse reactions (ADRs).
- A study examined 75 AIDS patients with PJP who received TMP/SMX, finding that 40.3% experienced ADRs, primarily skin rash and liver function impairment, mostly within the first two weeks of treatment.
- Risk factors linked to ADRs included a daily TMP/SMX dose of 16 mg/kg or more and being 34 years or older.
Background: The risk factors, microbial etiology, differentiation, and clinical features of purulent and non-purulent cellulitis are not well defined in Taiwan.
Methods: We conducted a retrospective cohort study of hospitalized adults with cellulitis in Taiwan in 2013. The demographic characteristics, underlying diseases, clinical manifestations, laboratory and microbiological findings, treatments, and outcomes were compared for patients with purulent and non-purulent cellulitis.