Framework for Kidney Health Follow-Up Among Neonates With Critical Cardiac Disease: A Report From the Neonatal Kidney Health Consensus Workshop.

Acute kidney injury is common among neonates with critical cardiac disease. Risk factors and associations with kidney-related outcomes are heterogeneous and distinct from other neonates. As survival of children with critical cardiac disease increases to adulthood, the burden of chronic kidney disease is increasing.

Acute Pain Recognition from Facial Expression Videos using Vision Transformers.

Pain assessment is significant for patients and clinicians in diagnosis and treatment injuries and disease. It could facilitate a patient's treatment process by monitoring patients' pain levels in an accurate and regular manner. Automated detection of pain from facial expressions is a useful technique to assess pain of patients with communication disabilities.

EEG-based Estimation of Cognitive Workload Across Multiple Tasks.

Key to the efficacy of working in high-risk environments is the reliable estimation of the human's cognitive state for improving safety and to maintain high performance longer. In this study, we developed an experimental protocol in which participants completed three cognitive tasks under two different levels (High, Low) of workload. We then evaluated the effect of the different cognitive activities on EEG signals and its accuracy in predicting respective cognitive load.

EGFR mutation status affects intra-tumoural heterogeneity of PD-L1 expression but not agreement between assays in resectable non-small cell lung cancer.

Background: The predictive value of PD-L1 to select patients for immunotherapy in resectable NSCLC remains imprecise, confounded by different assays used across trials and intra-tumoural heterogeneity (ITH). We sought to compare the concordance between 3 PD-L1 antibodies stratified by EGFR mutation status, evaluate ITH and implications on survival outcomes.

Methods: Tissue microarrays were constructed from stage IA-IIIA NSCLC with 3 tumour cores per patient.

Current Approaches and Innovations in Managing Preeclampsia: Highlighting Maternal Health Disparities.

Preeclampsia (PE) is a major cause of maternal mortality and morbidity, affecting 3-6% of pregnancies worldwide and ranking among the top six causes of maternal deaths in the U.S. PE typically develops after 20 weeks of gestation and is characterized by new-onset hypertension and/or end-organ dysfunction, with or without proteinuria.