Publications by authors named "C M J van Kinschot"
Background: Lymph node metastases in papillary thyroid cancer (PTC) increase the risk for persistent and recurrent disease. Data on the predictive value of histopathological features of lymph node metastases, however, are inconsistent. The aim of this study was to evaluate the prognostic significance of known and new histopathological features of lymph node metastases in a well-defined cohort of PTC patients with clinically evident lymph node metastases.
View Article and Find Full Text PDFObjective: The aim of this Meta-analysis is to evaluate the impact of different treatment strategies for early postoperative hypoparathyroidism on hypocalcemia-related complications and long-term hypoparathyroidism.
Data Sources: Embase.com, MEDLINE, Web of Science Core Collection, Cochrane Central Register of Controlled Trials, and the top 100 references of Google Scholar were searched to September 20, 2022.
Article Synopsis
- The study evaluated a new symptom-based treatment algorithm for managing postthyroidectomy hypocalcemia compared to a traditional biochemically-based approach.
- The algorithm significantly reduced the number of patients needing calcium and/or alfacalcidol supplementation during the first year and at 12 months follow-up, without severe complications.
- While there was an increase in calcium-related hospital visits, the findings suggest a need for more personalized treatment strategies based on individual changes in parathyroid hormone levels.
Regional Collaboration and Trends in Clinical Management of Thyroid Cancer.
Otolaryngol Head Neck Surg
January 2024
Objective: This study examines the trends in the management of thyroid cancer and clinical outcomes in the Southwestern region of The Netherlands from 2010 to 2021, where a regional collaborative network has been implemented in January 2016.
Study Design: Retrospective cohort study.
Setting: This study encompasses all patients diagnosed with thyroid cancer of any subtype between January 2010 and June 2021 in 10 collaborating hospitals in the Southwestern region of The Netherlands.
Background: Active surveillance is propagated as an alternative for hemithyroidectomy in the management of Bethesda III thyroid nodules.
Methods: A cross-sectional survey questioned respondents on their willingness to accept risks related to active surveillance and hemithyroidectomy.
Results: In case of active surveillance, respondents (129 patients, 46 clinicians, and 66 healthy controls) were willing to accept a risk of 10%-15% for thyroid cancer and 15% for needing more extensive surgery in the future.