Publications by authors named "C M Hannigan"
In this multicenter phase Ib trial, we investigated the combination of CPX-351 and gemtuzumab ozogamicin (GO) in relapsed/refractory acute myeloid leukemia (AML). Cohort A received CPX-351 plus a single dose of GO, while cohort B received two doses of GO. Thirteen participants received investigational treatment.
View Article and Find Full Text PDFBefriending services are often delivered to older adults with a view to improving social connectedness, but they may also lead to improved health. The objective of the current study was to explore potential mechanisms through which befriending services might impact the health of older adults. Data were collected from 13 befriendee-befriender dyads ( = 26), using a constructivist grounded theory and dyadic analytic approach.
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- A dementia research prioritisation exercise was conducted in Ireland due to insufficient information on key research areas, involving an online survey of professionals and workshops with individuals living with dementia and their family caregivers.
- The survey gathered feedback from 108 professionals, revealing that most priorities centered around enhancing the delivery and quality of care, alongside improving diagnosis and treatment methods for dementia.
- The results aim to guide policymakers and researchers in directing limited resources towards impactful dementia research that meets the needs of those affected by the condition.
Bladder cancer is one of the most commonly diagnosed genitourinary malignancies. For many years, the primary treatment for metastatic urothelial cancer (mUC) was predicated on the use of platinum-based chemotherapy. More recently, immune checkpoint inhibitors (ICIs) were approved by regulatory agencies such as the US FDA for use in both the first- and second-line settings.
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